Giulio Tononi is a neuroscientist and psychiatrist who holds the David P. White Chair in Sleep Medicine, as well as a Distinguished Chair in Consciousness Science, at the University of Wisconsin. He is best known for his Integrated Information Theory (IIT), a mathematical theory of consciousness, which he has proposed since 2004. WebGiulio Tononi (Italian: [ˈdʒuːljo toˈnoːni]) is a neuroscientist and psychiatrist who holds the David P. White Chair in Sleep Medicine, as well as a Distinguished Chair in Consciousness …

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The synaptotropic hypothesis, also called the synaptotrophic hypothesis, is a neurobiological hypothesis of neuronal growth and synapse formation. The hypothesis was first formulated by J.E. Vaughn in 1988, and remains a focus of current research efforts. The synaptotropic hypothesis proposes that input from a presynaptic to a postsynaptic cell (and maturation of excitatory synaptic inputs) eventually can change the course of synapse formation at dendritic and axonal ar… WebJun 24, 2011 · Sleep is present in every species that has been carefully studied (), including Drosophila melanogaster (2, 3), but its functions remain elusive.Increasing evidence … drakor unicorn

Sleep and synaptic down‐selection - Wiley Online Library

WebFeb 1, 2006 · According to the present hypothesis, Process S describes the process of synaptic homeostasis. Specifically, the curve in Fig. 1 can be interpreted as reflecting how the total amount of synaptic strength in the cerebral cortex (and possibly other brain structures) changes as a function of wakefulness and sleep. Thus, the hypothesis claims … WebJan 8, 2014 · The synaptic homeostasis hypothesis (SHY) proposes that sleep is the price the brain pays for plasticity. During a waking episode, learning statistical regularities … WebAggregation of amyloid-β (Aβ) peptide, glutamatergic neurotransmission, cholinergic hypothesis, tau protein, and the involvement of oxidative stress and calcium are considered as the theory about the pathogenesis of AD (Sanabria-Castro et al., 2024). The accumulation of Aβ has a role in AD pathogenesis) (Afshar et al., 2024; Selkoe, 2001). drakor voice 1